There are 49 Football Bowl Subdivision matchups on the Week 6 schedule, with Marshall (-1.5) among the best bets versus the spread, according to our projections. For more tips, including parlay opportunities, see below.

See insights and computer predictions for that matchup and more below.

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College Football Computer Picks – Best Spread Bets

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Pick: Marshall -1.5 vs. Appalachian State

• Matchup: Appalachian State Mountaineers at Marshall Thundering Herd
• Projected Winner & Margin: Marshall by 22.6 points
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Pick: Boise State -27.5 vs. Utah State

• Matchup: Utah State Aggies at Boise State Broncos
• Projected Winner & Margin: Boise State by 47.2 points
• Time: 7:00 PM ET
• Date: Oct. 5
• TV Channel: Fox Sports 2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Army -10.5 vs. Tulsa

• Matchup: Army Black Knights at Tulsa Golden Hurricane
• Projected Winner & Margin: Army by 28 points
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Charlotte +7.5 vs. East Carolina

• Matchup: East Carolina Pirates at Charlotte 49ers
• Projected Winner & Margin: Charlotte by 9.7 points
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Duke +8.5 vs. Georgia Tech

• Matchup: Duke Blue Devils at Georgia Tech Yellow Jackets
• Projected Winner & Margin: Duke by 6.7 points
• Time: 8:00 PM ET
• Date: Oct. 5
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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College Football Computer Picks – Best Total Bets

Over 35.5 – Navy vs. Air Force

• Matchup: Navy Midshipmen at Air Force Falcons
• Projected Total: 52.7 points
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo

Under 46.5 – Hawaii vs. San Diego State

• Matchup: Hawaii Rainbow Warriors at San Diego State Aztecs
• Projected Total: 35.8 points
• Time: 8:00 PM ET
• Date: Oct. 5
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 48.5 – James Madison vs. Louisiana-Monroe

• Matchup: James Madison Dukes at Louisiana-Monroe Warhawks
• Projected Total: 56.8 points
• Time: 7:00 PM ET
• Date: Oct. 5
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 54.5 – Alabama vs. Vanderbilt

• Matchup: Alabama Crimson Tide at Vanderbilt Commodores
• Projected Total: 62 points
• Time: 4:15 PM ET
• Date: Oct. 5
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 54.5 – Wake Forest vs. North Carolina State

• Matchup: Wake Forest Demon Deacons at North Carolina State Wolfpack
• Projected Total: 61.8 points
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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